Dr Marion McElwee
- Research Project Support (Virology)
telephone:
01413302988
email:
[email protected]
Centre for Virus Research, Sir Michael Stoker building, 464 Bearsden Rd, Glasgow, G61 1hq
Research interests
Member of the Bhella Group.
Publications
2025
Furnon, W. et al. (2025) Phenotypic evolution of SARS-CoV-2 spike during the COVID-19 pandemic. Nature Microbiology, 10, pp. 77-93. (doi: 10.1038/s41564-024-01878-5) (PMID:39753670) (PMCID:PMC11726466)
2024
Samolej, J., Correa Mendonca, D. , Upfold, N. , McElwee, M., Landsberger, M., Yakimovich, A., Patel, A. H. , Strang, B. L. and Mercer, J. (2024) Bisbenzimide compounds inhibit the replication of prototype and pandemic potential poxviruses. Microbiology Spectrum, 12(4), e04072-23. (doi: 10.1128/spectrum.04072-23) (PMID:38376353) (PMCID:PMC10986486)
2021
Rihn, S. J. et al. (2021) A plasmid DNA-launched SARS-CoV-2 reverse genetics system and coronavirus toolkit for COVID-19 research. PLoS Biology, 19(2), e3001091. (doi: 10.1371/journal.pbio.3001091) (PMID:33630831) (PMCID:PMC7906417)
2020
Vijayakrishnan, S. , McElwee, M., Loney, C. , Rixon, F. and Bhella, D. (2020) In situ structure of virus capsids within cell nuclei by correlative light and cryo-electron tomography. Scientific Reports, 10, 17596. (doi: 10.1038/s41598-020-74104-x) (PMID:33077791) (PMCID:PMC7572381)
2019
Saiz-Ros, N. et al. (2019) Host vesicle fusion protein VAPB contributes to the nuclear egress stage of herpes simplex virus type-1 (HSV-1) replication. Cells, 8(2), 120. (doi: 10.3390/cells8020120)
Conley, M. J. , McElwee, M., Azmi, L., Gabrielsen, M. , Byron, O. , Goodfellow, I. G. and Bhella, D. (2019) Calicivirus VP2 forms a portal-like assembly following receptor engagement. Nature, 565(7739), pp. 377-381. (doi: 10.1038/s41586-018-0852-1) (PMID:30626974)
2018
McElwee, M., Vijayakrishnan, S. , Rixon, F. and Bhella, D. (2018) Structure of the herpes-simplex virus portal-vertex. PLoS Biology, 16(6), e2006191. (doi: 10.1371/journal.pbio.2006191) (PMID:29924793) (PMCID:PMC6028144)
2015
Fan, W. H., Robertson, A. P.E., McElwee, M., Bhella, D. , Rixon, F. J. and Lauder, R. (2015) The large tegument protein pUL36 is essential for formation of the capsid vertex-specific component at the capsid-tegument interface of herpes simplex virus 1. Journal of Virology, 89(3), pp. 1502-1511. (doi: 10.1128/JVI.02887-14) (PMID:25410861) (PMCID:PMC4300765)
2013
McElwee, M., Beilstein, F., Labetoulle, M., Rixon, F.J. and Pasdeloup, D. (2013) Dystonin/bpag1 promotes plus-end-directed transport of herpes simplex virus 1 capsids on microtubules during entry. Journal of Virology, 87(20), pp. 11008-11018. (doi: 10.1128/JVI.01633-13)
Pasdeloup, D., McElwee, M., Beilstein, F., Labetoulle, M. and Rixon, F.J. (2013) Herpesvirus tegument protein pUL37 interacts with dystonin/BPAG1 to promote capsid transport on microtubules during egress. Journal of Virology, 87(5), pp. 2857-2867. (doi: 10.1128/JVI.02676-12) (PMID:23269794) (PMCID:PMC3571392)
2010
Pasdeloup, D., Beilstein, F., Roberts, A.P.E., McElwee, M., McNab, D. and Rixon, F.J. (2010) Inner tegument protein pUL37 of herpes simplex virus type 1 is involved in directing capsids to the trans-Golgi network for envelopment. Journal of General Virology, 91(9), pp. 2145-2151. (doi: 10.1099/vir.0.022053-0) (PMID:20505007) (PMCID:PMC3066548)
2006
Hope, R.G., McElwee, M.J. and McLauchlan, J. (2006) Efficient cleavage by signal peptide peptidase requires residues within the signal peptide between the core and E1 proteins of hepatitis C virus strain J1. Journal of General Virology, 87(3), pp. 623-627. (doi: 10.1099/vir.0.81371-0) (PMID:16476983)
2005
Targett-Adams, P., McElwee, M.J., Ehrenborg, E., Gustafsson, M.C., Palmer, C.N. and McLauchlan, J. (2005) A PPAR response element regulates transcription of the gene for human adipose differentiation-related protein. BBA: Gene Structure and Expression, 1728(1-2), pp. 95-104. (doi: 10.1016/j.bbaexp.2005.01.017)
Articles
Furnon, W. et al. (2025) Phenotypic evolution of SARS-CoV-2 spike during the COVID-19 pandemic. Nature Microbiology, 10, pp. 77-93. (doi: 10.1038/s41564-024-01878-5) (PMID:39753670) (PMCID:PMC11726466)
Samolej, J., Correa Mendonca, D. , Upfold, N. , McElwee, M., Landsberger, M., Yakimovich, A., Patel, A. H. , Strang, B. L. and Mercer, J. (2024) Bisbenzimide compounds inhibit the replication of prototype and pandemic potential poxviruses. Microbiology Spectrum, 12(4), e04072-23. (doi: 10.1128/spectrum.04072-23) (PMID:38376353) (PMCID:PMC10986486)
Rihn, S. J. et al. (2021) A plasmid DNA-launched SARS-CoV-2 reverse genetics system and coronavirus toolkit for COVID-19 research. PLoS Biology, 19(2), e3001091. (doi: 10.1371/journal.pbio.3001091) (PMID:33630831) (PMCID:PMC7906417)
Vijayakrishnan, S. , McElwee, M., Loney, C. , Rixon, F. and Bhella, D. (2020) In situ structure of virus capsids within cell nuclei by correlative light and cryo-electron tomography. Scientific Reports, 10, 17596. (doi: 10.1038/s41598-020-74104-x) (PMID:33077791) (PMCID:PMC7572381)
Saiz-Ros, N. et al. (2019) Host vesicle fusion protein VAPB contributes to the nuclear egress stage of herpes simplex virus type-1 (HSV-1) replication. Cells, 8(2), 120. (doi: 10.3390/cells8020120)
Conley, M. J. , McElwee, M., Azmi, L., Gabrielsen, M. , Byron, O. , Goodfellow, I. G. and Bhella, D. (2019) Calicivirus VP2 forms a portal-like assembly following receptor engagement. Nature, 565(7739), pp. 377-381. (doi: 10.1038/s41586-018-0852-1) (PMID:30626974)
McElwee, M., Vijayakrishnan, S. , Rixon, F. and Bhella, D. (2018) Structure of the herpes-simplex virus portal-vertex. PLoS Biology, 16(6), e2006191. (doi: 10.1371/journal.pbio.2006191) (PMID:29924793) (PMCID:PMC6028144)
Fan, W. H., Robertson, A. P.E., McElwee, M., Bhella, D. , Rixon, F. J. and Lauder, R. (2015) The large tegument protein pUL36 is essential for formation of the capsid vertex-specific component at the capsid-tegument interface of herpes simplex virus 1. Journal of Virology, 89(3), pp. 1502-1511. (doi: 10.1128/JVI.02887-14) (PMID:25410861) (PMCID:PMC4300765)
McElwee, M., Beilstein, F., Labetoulle, M., Rixon, F.J. and Pasdeloup, D. (2013) Dystonin/bpag1 promotes plus-end-directed transport of herpes simplex virus 1 capsids on microtubules during entry. Journal of Virology, 87(20), pp. 11008-11018. (doi: 10.1128/JVI.01633-13)
Pasdeloup, D., McElwee, M., Beilstein, F., Labetoulle, M. and Rixon, F.J. (2013) Herpesvirus tegument protein pUL37 interacts with dystonin/BPAG1 to promote capsid transport on microtubules during egress. Journal of Virology, 87(5), pp. 2857-2867. (doi: 10.1128/JVI.02676-12) (PMID:23269794) (PMCID:PMC3571392)
Pasdeloup, D., Beilstein, F., Roberts, A.P.E., McElwee, M., McNab, D. and Rixon, F.J. (2010) Inner tegument protein pUL37 of herpes simplex virus type 1 is involved in directing capsids to the trans-Golgi network for envelopment. Journal of General Virology, 91(9), pp. 2145-2151. (doi: 10.1099/vir.0.022053-0) (PMID:20505007) (PMCID:PMC3066548)
Hope, R.G., McElwee, M.J. and McLauchlan, J. (2006) Efficient cleavage by signal peptide peptidase requires residues within the signal peptide between the core and E1 proteins of hepatitis C virus strain J1. Journal of General Virology, 87(3), pp. 623-627. (doi: 10.1099/vir.0.81371-0) (PMID:16476983)
Targett-Adams, P., McElwee, M.J., Ehrenborg, E., Gustafsson, M.C., Palmer, C.N. and McLauchlan, J. (2005) A PPAR response element regulates transcription of the gene for human adipose differentiation-related protein. BBA: Gene Structure and Expression, 1728(1-2), pp. 95-104. (doi: 10.1016/j.bbaexp.2005.01.017)
Research datasets
2024
Furnon, W. , Cowton, V. M., De Lorenzo, G. , Orton, R. , Herder, V. , Cantoni, D. , Ilia, G., Correa Mendonca, D. , Kerr, K., Allan, J., Upfold, N. , Meehan, G. R. , Bakshi, S., Das, U. R., Molina Arias, S., McElwee, M., Little, S., Logan, N., Kwok, K. , Smollett, K. , Willett, B. , Da Silva Filipe, A. , Robertson, D. L. , Grove, J. , Patel, A. H. and Palmarini, M. (2024) Phenotypic evolution of SARS-CoV-2 spike throughout the COVID-19 pandemic. [Data Collection]
